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Inhaltsverzeichnise (Kurzversion) - Table of Contents (short version)

 

Systems Biology of Apoptosis

Mathematical Modeling of the Wnt-Pathway

Modeling Signaling Pathways  A Yeast Approach

Mechanistic and Modular Approaches to Modeling and Inference of Cellular Regulatory Networks

Scientific and Technical Challenges for Systems Biology

Integration of Metabolic and Signaling Networks

From Isolation to Integration, a Systems Biology Approach for Building the Silicon Cell

Whats Systems Biology: From Genes to Function and Back

Systems Biology: Recent Developments and New Trends

A Modular Systems Biology Analysis of the Cell Cycle Entrance into S Phase

Metabolic Control Analysis

Mesoscopic Kinetics and its Applications in Protein Synthesis

E. coli Glycolysis

Kinetic Modeling of the E. coli Metabolism

No Music without Melody: How to Understand Biochemical Systems by Understanding Their Dynamics

Systems Biology of the Yeast Cell Cycle Engine

Quantification of in vivo Molecular Fluxes: A Key Methodology for Metabolic Systems Biology

Modeling the E. coli cell: The Need for Computing, Cooperation, and Consortia.

 

Beschreibung

The wealth of genomic and post-genomic data needs to be structured so that the understanding of complex cellular processes can be achieved by creating computational models able to describe and predict phenotypes at the cell or organism level in health and disease. This book provides a detailed presentation of systems biology studies that are paving the way towards the above-mentioned goal and discusses the most efficient experimental and computational strategies for this purpose. The potential benefits for bioindustry, in particular the discovery of new drugs and better management, are also presented.