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Genetics and genomics in medicine

second edition
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Author: Search for this author Strachan, Tom (author); Lucassen, Anneke (author)
Year: 2023
Publisher: Boca Raton, Oxon, CRC Press
Media group: Ausleihbestand
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Content

The second edition of this textbook written for undergraduate students, graduate students, and medical researchers, Genetics and Genomics in Medicine explains the science behind the uses of genetics and genomics in medicine today.Maintaining the features that made the first edition so popular, this second edition has been thoroughly updated in line with the latest developments in the field. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. Cancers are given a dedicated chapter that includes the latest insights into its molecular basis and approaches to its detection gained from cancer genomics. Key features· Comprehensive and integrated account of how genetics and genomics affect the entire spectrum of human health and disease· Exquisite artwork illuminates the key concepts and mechanisms· Summary points at the end of each chapter help to consolidate learning· For each chapter, an abundance of annotated further reading provide readers with direction for further study· Specific topics, including multiple examples of clinical disorders, molecular mechanisms, and technological advances, are profiled in boxes throughout the text· Ethics chapter revised and expanded reflecting importance of this area and its associated social and legal challenges· Online question bank tests understanding
 
1. Fundamentals of DNA, Chromosomes, and Cells ; 2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization ; 3. Principles Underlying Core DNA Technologies ; 4. Principles of Genetic Variation ; 5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies ; 6. Principles of Gene Regulation and Epigenetics ; 7. How Genetic Variation in DNA and Chromosomes Causes Disease; 8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease; 9. Genetic Approaches to Treating Disease ; 10. Cancer Genetics and Genomics; 11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects;

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Details

Author: Search for this author Strachan, Tom (author); Lucassen, Anneke (author)
Statement of Responsibility: Tom Strachan ; Anneke Lucassen
Year: 2023
Publisher: Boca Raton, Oxon, CRC Press
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Classification: Search for this systematic GE-40
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ISBN: 978-0-367-49081-2
ISBN (2nd): 978-0367-49082-9
Description: second edition, XVII, 534 S. , Illustrationen, graphische Darstellungen
Tags: medical genetics; Biotechnology; Genetics and Genomics.
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Language: Englisch
Original title: Genetics and genomics in medicine
Footnote: Literaturangaben
Media group: Ausleihbestand