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Computational genomics with R

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Author: Search for this author Akalin, Altuna (author)
Year: [2021]
Publisher: Boca Raton, FL ; Abingdon, CRC Press, an imprint of Taylor & Francis Group, LLC
Media group: Ausleihbestand
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Content

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology.
 
After reading:
 
You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages.
You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data.
You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation.
You will know the basics of processing and quality checking high-throughput sequencing data.
You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites.
You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization.
You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq.
You will know basic techniques for integrating and interpreting multi-omics datasets.

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Details

Author: Search for this author Akalin, Altuna (author)
Statement of Responsibility: Altuna Akalin, with the assistance of Verdan Franke, Bora Uyar, Jonathan Ronen
Year: [2021]
Publisher: Boca Raton, FL ; Abingdon, CRC Press, an imprint of Taylor & Francis Group, LLC
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Classification: Search for this systematic GE-40, GE-30, MA-20
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ISBN: 9781498781855
ISBN (2nd): 1498781853
Description: xxii, 440 Seiten, Illustrationen, Diagramme
Tags: Datenverarbeitung, Genetik Methoden, Molekulare Genetik
Language: Englisch
Original title: Computational genomics with R
Media group: Ausleihbestand