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Molecular mechanisms of inflammation

induction, resolution and escape by Helicobacter pylori
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Jahr: [2019]
Verlag: Cham, Springer Nature Switzerland AG
Reihe: Current topics in microbiology and immunology; 421
Mediengruppe: Serien
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Inhalt

This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection.
 
This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.

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Suche nach diesem Verfasser
Verfasserangabe: Steffen Backert, editor. Responsible series editor: Klaus Aktories
Jahr: [2019]
Verlag: Cham, Springer Nature Switzerland AG
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Systematik: Suche nach dieser Systematik MB-40, ZB-90
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ISBN: 9783030151379
2. ISBN: 3030151379
Beschreibung: XXIV, 359 Seiten, Diagramme, Illustrationen
Reihe: Current topics in microbiology and immunology; 421
Schlagwörter: Immunbiologie; Medizinische Mikrobiologie
Beteiligte Personen: Suche nach dieser Beteiligten Person Backert, Steffen (Herausgeber); Aktories, Klaus (Mitwirkender)
Sprache: Englisch
Originaltitel: Molecular mechanisms of inflammation
Mediengruppe: Serien