Andre Bernards, Ras Superfamily and Interacting Proteins Database. Pages 1-9.
Adam Shutes and Channing J. Der, Real -Time In Vitro Measurement of Intrinsic and Ras GAP -Mediated GTP Hydrolysis. Pages 9-22.
Nancy Ratner, Jon P. Williams, Jennifer J. Kordich and Haesun A. Kim, Schwann Cell Preparation from Single Mouse Embryos: Analyses of Neurofibromin Function in Schwann Cells. Pages 22-33.
Michael A. Fischbach and Jeffrey Settleman, Regulation of the Nucleotide State of Oncogenic Ras Proteins by Nucleoside Diphosphate Kinase. Pages 33-45.
Yong Li, Ken Inoki, Haris Vikis and Kun -Liang Guan, Measurements of TSC2 GAP Activity Toward Rheb. Pages 46-54.
Kyriacos Felekkis, Lawrence A. Quilliam and Adam Lerner, Characterization of AND -34 Function and Signaling. Pages 55-63.
Sabine Kupzig, Dalila Bouyoucef, Gyles E. Cozier and Peter J. Cullen, Studying the Spatial and Temporal Regulation of Ras GTPase -Activating Proteins. Pages 64-82.
Que T. Lambert and Gary W. Reuther, Activation of Ras Proteins by Ras Guanine Nucleotide Releasing Protein Family Members. Pages 82-98.
Hironori Edamatsu, Takaya Satoh and Tohru Kataoka, Ras and Rap1 Activation of PLC[var epsilon] Lipase Activity. Pages 99-107.
Lawrence A. Quilliam, Specificity and Expression of RalGPS as RalGEFs. Pages 108-114.
Laura A. Martello and Angel Pellicer, Biochemical and Biological Analyses of Rgr RalGEF Oncogene. Pages 115-128.
Trever G. Bivona, Steven Quatela and Mark R. Philips, Analysis of Ras Activation in Living Cells with GFP -RBD. Pages 128-143.
Annika W. Svensson, Patrick J. Casey, Stephen G. Young and Martin O. Bergo, Genetic and Pharmacologic Analyses of the Role of Icmt in Ras Membrane Association and Function. Pages 144-159.
Holger Rehmann, Characterization of the Activation of the Rap -Specific Exchange Factor Epac by Cyclic Nucleotides. Pages 159-173.
H. Bea Kuiperij, Holger Rehmann and Fried J.T. Zwartkruis, Biochemistry of the Rap -Specific Guanine Nucleotide Exchange Factors PDZ -GEF1 and -2. Pages 174-186.
Pablo Rodriguez -Viciana and Frank McCormick, Characterization of Interactions Between Ras Family GTPases and Their Effectors. Pages 187-194.
Paul M. Campbell, Anurag Singh, Falina J. Williams, Karen Frantz, Aylin S. ïœlfïœ, Grant G. Kelley and Channing J. Der, Genetic and Pharmacologic Dissection of Ras Effector Utilization in Oncogenesis. Pages 195-217.
Richard Wooster, Andrew P. Futreal and Michael R. Stratton, Sequencing Analysis of BRAF Mutations in Human Cancers. Pages 218-224.
Daniel A. Ritt, Ira O. Daar and Deborah K. Morrison, KSR Regulation of the Raf -MEK -ERK Cascade. Pages 224-237.
Sharon A. Matheny and Michael A. White, Ras -Sensitive IMP Modulation of the Raf/MEK/ERK Cascade Through KSR1. Pages 237-247.
Suzanne Hagan, Rey Garcia, Amardeep Dhillon and Walter Kolch, Raf Kinase Inhibitor Protein Regulation of Raf and MAPK Signaling. Pages 248-259.
Angelique W. Whitehurst and Michael A. White, Harnessing RNAi for Analyses of Ras Signaling and Transformation. Pages 259-268.
Kristin Strumane, Tomasz P. Rygiel and John G. Collard, The Rac Activator Tiam1 and Ras -Induced Oncogenesis. Pages 269-281.
Takaya Satoh, Hironori Edamatsu and Tohru Kataoka, Phospholipase C[epsilon] Guanine Nucleotide Exchange Factor Activity and Activation of Rap1. Pages 281-290.
Joseph Avruch, Maria Praskova, Sara Ortiz -Vega, Matthew Liu and Xian -Feng Zhang, Nore1 and RASSF1 Regulation of Cell Proliferation and of the MST1/2 Kinases. Pages 290-310.
Michele D. Vos and Geoffrey J. Clark, RASSF Family Proteins and Ras Transformation. Pages 311-322.
Natalia Mitin, Stephen F. Konieczny andElizabeth J. Taparowsky, RAS and the RAIN/RasIP1 Effector. Pages 322-335.
Joanne M. Bliss, Byrappa Venkatesh and John Colicelli, The RIN Family of Ras Effectors. Pages 335-344.
Esther Lafuente and Vassiliki A. Boussiotis, Rap1 Regulation of RIAM and Cell Adhesion. Pages 345-358.
Yasuyuki Fujita, Catherine Hogan and Vania M.M. Braga, Regulation of Cell-Cell Adhesion by Rap1. Pages 359-372.
Oleg I. Tchernitsa, Christine Sers, Anita Geflitter and Reinhold Schïœfer, Effects of Ras Signaling on Gene Expression Analyzed by Customized Microarrays. Pages 373-387.
John K. Westwick and Stephen W. Michnick, Protein -Fragment Complementation Assays (PCA) in Small GTPase Research and Drug Discovery. Pages 388-401.
Michael G. Backlund, Jason R. Mann, Dingzhi Wang and Raymond N. DuBois, Ras Up -Regulation of Cyclooxygenase -2. Pages 401-410.
G.L. Prasad, Regulation of the Expression of Tropomyosins and Actin Cytoskeleton by ras Transformation. Pages 410-422.
Krishna Murthi Vasudevan, Padhma Ranganathan and Vivek M. Rangnekar, Regulation of Par -4 by Oncogenic Ras. Pages 422-442.
Parthive H. Patel and Fuyuhiko Tamanoi, Using Drosophila and Yeast Genetics to Investigate a Role for the Rheb GTPase in Cell Growth. Pages 443-454.
Yinhua Yu, Robert Luo, Zhen Lu, Wei Wei Feng, Donna Badgwell, Jean -Pierre Issa, Daniel G. Rosen, Jinsong Liu and Robert C. Bast, Jr., Biochemistry and Biology of ARHI (DIRAS3), an Imprinted Tumor Suppressor Gene Whose Expression Is Lost in Ovarian and Breast Cancers. Pages 455-468.
Yvona Ward and Kathleen Kelly, Gem Protein Signaling and Regulation. Pages 468-483.
Douglas A. Andres, Shawn M. Crump, Robert N. Correll, Jonathan Satin and Brian S. Finlin, Analyses of Rem/RGK Signaling and Biological Activity. Pages 484-498.
Douglas A. Andres, Jennifer L. Rudolph, Tomoko Sengoku and Geng -Xian Shi, Analysis of Rit Signaling and Biological Activity. Pages 499-512.
Megan D. Key, Douglas A. Andres, Channing J. Der and Gretchen A. Repasky, Characterization of RERG: An Estrogen -Regulated Tumor Suppressor Gene. Pages 513-527.
Tom Huxford and Gourisankar Ghosh, Inhibition of Transcription Factor NF -[kappa]B Activation by [kappa]B -Ras. Pages 527-534.
Juan Bernal and Piero Crespo, Analysis of Rhes Activation State and Effector Function. Pages 535-542.
Jessie Hanrahan and John Blenis, Rheb Activation of mTOR and S6K1 Signaling. Pages 542-555.
Antonio T. Baines, Kian -Huat Lim, Janiel M. Shields, John M. Lambert, Christopher M. Counter, Channing J. Der and Adrienne D. Cox, Use of Retrovirus Expression of Interfering RNA to Determine the Contribution of Activated K -Ras and Ras Effector Expression to Human Tumor Cell Growth. Pages 556-574.
Anastacia C. Berzat, Donita C. Brady, James J. Fiordalisi and Adrienne D. Cox, Using Inhibitors of Prenylation to Block Localization and Transforming Activity. Pages 575-597.
Lila Adnane, Pamela A. Trail, Ian Taylor and Scott M. Wilhelm, Sorafenib (BAY 43 -9006, Nexavarïœ), a Dual -Action Inhibitor That Targets RAF/MEK/ERK Pathway in Tumor Cells and Tyrosine Kinases VEGFR/PDGFR in Tumor Vasculature. Pages 597-612.
Vladimir Khazak, Juran Kato -Stankiewicz, Fuyu Tamanoi and Erica A. Golemis, Yeast Screens for Inhibitors of Ras-Raf Interaction and Characterization of MCP Inhibitors of Ras-Raf Interaction. Pages 612-629.
Sung Chan Kim, Yoonjung Kho, Deb Barma, John Falck and Yingming Zhao, A Tagging -via -Substrate Technology for Genome -Wide Detection and Identification of Farnesylated Proteins. Pages 629-637.
Kevin M. O'Hayer and Christopher M. Counter, A Genetically Defined Normal Human Somatic Cell System to Study Ras Oncogenesis In Vivo and In Vitro. Pages 637-647.
Zaruhi Poghosyan and David Wynford -Thomas, Analysis of Ras Transformation of Human Thyroid Epithelial Cells. Pages 648-660.
Daniel G. Rosen, Gong Yang, Robert C. Bast, Jr. and Jinsong Liu, Use of Ras -Transformed Human Ovarian Surface Epithelial Cells as a Model for Studying Ovarian Cancer. Pages 660-676.
Pedro Antonio Pïœrez -Mancera and David A. Tuveson, Physiological Analysis of Oncogenic K -Ras. Pages 676-690.
Jason A. Reuter and Paul A. Khavari, Use of Conditionally Active Ras Fusion Proteins to Study Epidermal Growth, Differentiation, and Neoplasia. Pages 691-702.
Cristina Agbunag, Kyoung Eun Lee, Serena Buontempo and Dafna Bar -Sagi, Pancreatic Duct Epithelial Cell Isolation and Cultivation in Two -Dimensional and Three -Dimensional Culture Systems. Pages 703-710.
Lucy C. Firth, Wei Li, Hui Zhang and Nicholas E. Baker, Analyses of RAS Regulation of Eye Development in Drosophila melanogaster. Pages 711-721.