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GPCRs

structure, function, and drug discovery
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Year: [2020]
Publisher: London, San Diego, CA, Cambridge, MA, Oxford, Academic Press, an imprint of Elsevier
Media group: Ausleihbestand
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Content

GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth.

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Statement of Responsibility: edited by Beata Jastrzebska, Paul S.-H. Park
Year: [2020]
Publisher: London, San Diego, CA, Cambridge, MA, Oxford, Academic Press, an imprint of Elsevier
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Classification: Search for this systematic NA-30, ME-30, ME-20
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ISBN: 9780128162286
ISBN (2nd): 0128162287
Description: xvii, 481 Seiten, Illustrationen
Tags: Proteine; Pharmazie; Pharmakologie
Participating parties: Search for this character Jastrzebska, Beata (editor); Park, Paul S.-H. (editor)
Language: Englisch
Original title: GPCRs
Media group: Ausleihbestand