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Cell-based assays using iPSCs for drug development and testing

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Year: [2019]
Publisher: New York, NY, Humana Press, Springer Science+Business LLC, part of Springer Nature
Series: Methods in molecular biology; 1994
Media group: Ausleihbestand
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Branch: Hauptstelle Locations: ZB-130 130 Status: available Reservations: 0 Due date: Barcode: 00304891 Floor plans: Floor plan Lending note:

Content

The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
 
Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.

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Statement of Responsibility: edited by Carl-Fredrik Mandenius, Division of Biotechnology, Department of Physics, Chemistry and Biology (IFM), Linköping University, Linköping, Sweden, James A. Ross, Tissue Injury and Repair Group, University of Edinburgh, Edinburgh, UK
Year: [2019]
Publisher: New York, NY, Humana Press, Springer Science+Business LLC, part of Springer Nature
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Classification: Search for this systematic ZB-130, ME-30
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ISBN: 9781493994762
ISBN (2nd): 149399476X
Description: xiv, 266 Seiten, Diagramme, Illlustrationen
Series: Methods in molecular biology; 1994
Tags: Zellbiologie Methoden; Pharmazie
Participating parties: Search for this character Mandenius, Carl-Fredrik (editor); Ross, James A. (editor)
Language: Englisch
Original title: Cell-based assays using iPSCs for drug development and testing
Media group: Ausleihbestand