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Fc mediated activity of antibodies
structural and functional diversity
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Year: [2019]
Publisher: Cham, Springer Nature Switzerland AG
Media group: Serien
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This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
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Details
Statement of Responsibility: Jeffrey V. Ravetch, Falk Nimmerjahn, editors. Responsible series editor: Rino Rappuoli
Year: [2019]
Publisher: Cham, Springer Nature Switzerland AG
Classification: MB-40, ZB-90
ISBN: 9783030310523
ISBN (2nd): 3030310523
Description: vii, 150 Seiten, Diagramme
Tags: Immunbiologie, Medizinische Mikrobiologie
Language: Englisch
Original title: Fc mediated activity of antibodies
Media group: Serien

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