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HIV-1 latency

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Year: [2018]
Publisher: Cham, Springer Nature Switzerland AG
Series: Current topics in microbiology and immunology; 417
Media group: Serien
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Content

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

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Statement of Responsibility: Guido Silvestri, Mathias Lichterfeld, editors. Responsible series editor: Michael B. A. Oldstone
Year: [2018]
Publisher: Cham, Springer Nature Switzerland AG
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Classification: Search for this systematic MB-40, ZB-90
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ISBN: 9783030028152
ISBN (2nd): 3030028151
Description: vii, 248 Seiten, Diagramme
Series: Current topics in microbiology and immunology; 417
Tags: Medizinische Mikrobiologie; Immunbiologie
Language: Englisch
Original title: HIV-1 latency
Media group: Serien