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Viruses, genes, and cancer

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Year: [2017]
Publisher: Cham, Springer International Publishing AG
Series: Current topics in microbiology and immunology; 407
Media group: Serien
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Branch: Hauptstelle Locations: Serie Status: available Reservations: 0 Due date: Barcode: 00299740 Floor plans: Floor plan Lending note:

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This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

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Statement of Responsibility: Eric Hunter, Klaus Bister, editors. Responsible series editor: Richard W. Compans
Year: [2017]
Publisher: Cham, Springer International Publishing AG
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Classification: Search for this systematic ZB-100, VI-10
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ISBN: 9783319618036
ISBN (2nd): 3319618032
Description: xiii, 221 Seiten, Illustrationen, Diagramme
Series: Current topics in microbiology and immunology; 407
Tags: Transformierte Zellen; Virologie allgemein
Participating parties: Search for this character Hunter, Eric (editor); Bister, Klaus (editor); Compans, Richard W. (editor)
Language: Deutsch
Media group: Serien